MATERIAL and METHODS: In this retrospective study, clinical, laboratory, radiological and surgical data of 124 patients prediagnosed with pituitary adenoma who underwent surgery between January 2016 and December 2019 were evaluated. The patients" age, gender and symptoms were evaluated. Post-operative follow-up of the patients was performed by using contrast-enhanced MRI on the 1st day and the 3rd and 6th month after the surgery, and the tumor recurrence, regression or progression status was evaluated.

RESULTS: Of the 124 individuals, 57 were female, while 67 were male. The age range was between 20 and 79 years. The most common complaint was visual impairment. The size of the tumor was analyzed and found to be larger than 1 cm (macroadenoma) in 120 patients and less than 1 cm (microadenoma) in 4 patients. Pituitary macroadenomas between 11 and 30 mm were most commonly observed. Non-immunoreactive adenomas were found in 39 patients and immunoreactive pituitary adenomas in 85 patients. Transient diabetes insipidus was the most frequently encountered early postoperative complication.

CONCLUSION: Accurate perioperative care of patients undergoing the endoscopic endonasal transsphenoidal approach for a pituitary adenoma contributes to minimizing postoperative complications and maximizing therapeutic results. Endoscopic endonasal transsphenoidal surgery is a very successful approach in the treatment of pituitary adenomas. Anahtar Kelimeler : Pituitary gland, Pituitary adenoma, Transsphenoidal approach, Endonasal endoscopic approach, Complication